Colloidal Gold vs Fluorescence Lateral Flow Assay Platforms
Colloidal gold and fluorescence lateral flow assays are both important rapid diagnostic routes. Colloidal gold is mature and visually intuitive, while fluorescence is more suitable for instrument reading, higher sensitivity and quantitative output.
Colloidal gold
Colloidal gold assays are suitable for visual or optical colorimetric reading and routine rapid testing. Key concerns include labeling stability, color strength, background, running speed and consistency.
Fluorescence
Fluorescence assays rely on readers and focus on fluorescent bead coupling, background noise, reading window, linear range, instrument compatibility and stability.
FAQ
Is fluorescence always better?
Not always. Fluorescence offers sensitivity and readout advantages but requires instrumentation and systematic background control.
Can a colloidal gold project be upgraded?
Yes, but marker, strip materials, backing card, reader and method parameters need to be revalidated.
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